Cancer

Current options to treat cancer include surgery, chemotherapy, and radiotherapy; but will there ever be a cancer vaccine? Vaccines are a powerful method to prevent infectious diseases. They work by stimulating the immune system to mount a reaction against dangerous germs. The success of vaccines in controlling infectious diseases prompted scientists to explore their use
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Researchers evaluated an immunotherapy-chemotherapy combination cream in the prevention of skin cancer following precancerous lesions in sun-damaged skin.   Despite widespread awareness of the need to protect skin from the sun, squamous cell carcinoma (SCC) of the skin is the second most common cancer in the United States, and its incidence continues to rise. Skin
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Reading Time: 2 minutes A recent study explored the differences in risk-management behaviours between women of various races who are at high risk of developing breast cancer. Managing several medical conditions is largely influenced by personal, social, genetic, environmental, and psychological determinants of health. These factors vary by race, leading to racial disparities that are
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Reading Time: 3 minutes A recent study investigated tongue microbial populations as a potential tool for the early detection of pancreatic cancer.   Pancreatic cancer is among the deadliest cancer types. This disease causes hundreds of thousands of deaths every year, ranking seventh for the number of fatalities from cancer. Pancreatic cancer occurs more often
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Reading Time: 3 minutes Researchers have observed increases in early-onset colorectal cancer. In a recent study, they determine its relation to obesity. Obesity is characterized by being overweight and specifically, having a BMI of 30 or greater.  According to Obesity Canada, obesity is a chronic illness that resembles diabetes mellitus (type 1 diabetes) and high
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Reading Time: 2 minutes Researchers from Purdue University in the United States developed a series of new compounds to treat acute myeloid leukemia and tested them in a preclinical study. According to the Canadian Cancer Society, over 1,300 Canadians were diagnosed with this aggressive leukemia in 2013, with nearly a thousand Canadians died from it.
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A recent study analyzing the receptor that leads to nausea could be crucial in the development of drugs to reduce chemotherapy side effects. Most currently used cancer drugs are known to cause many chemotherapy side effects. These unpleasant side effects are sensed through a class of receptors called neurokin 1 receptor (NK1R). Pharmacological targeting of these
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A recent study investigated why immunotherapy for breast cancer is not as effective as a cancer treatment. Despite the recent advancements in immunotherapy and the new era of personalized medicine to treat different forms of cancer, breast cancer has proven to be a difficult opponent for this new therapy. Previous trials have shown that immunotherapy
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Research shows promise towards understanding the underpinning cellular causes of skin cancer and its potential treatment.   The incidence of skin cancer is rising with cutaneous squamous cell carcinoma (cSCC), a form of non-melanoma skin cancer that is the second most common form of cancer in the United States. Of these, between 2-5% of patients
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Past methods for antitumor therapies have focused on enhancing systemic immune activity. Yale University researchers have highlighted developments in a more recent approach to cancer immunotherapy that may result in more effective treatments.   Since its inception, cancer research has largely been based on the premise of enhancement therapies: immune system boosting treatments that increase
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Many cancer patients find that they develop cognitive problems as they become ill. A new study found that aspirin could limit cognitive problems in mice with cancer. Almost half of cancer patients with solid tumors develop cognitive problems, including problems with learning, concentration, and memory. Some of these problems can remain decades after successful cancer
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Medical scientists in the United States have discovered the key protein responsible for childhood leukemia. They discussed their findings in Genes & Development. Childhood leukemia, the most common cancer of children in Canada, is a cancer of the white blood cells. Leukemia develops when abnormal white blood cells form in the bone marrow. These abnormal
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A small-molecule drug inhibitor called vismodegib successfully treated a dire case of infiltrative basal cell carcinoma. According to the authors, this case qualifies as a first to report a complete remission for this subset of skin cancer.   Basal cell carcinoma (BCC) is one of the most common types of skin cancer. For patients with
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  Human papillomavirus (HPV) is responsible for causing cervical cancer in many women worldwide, and successful screening programs have been accredited with helping to increase the capacity to identify and treat precancerous and pre-invasive disease. Quantitative methylation of the POU4F3 gene biomarker is a valuable tool for high-grade CIN detection.   Cervical cancer, caused by the human
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A recent study assessed the potential role of the fecal immunochemical test for colorectal cancer screening in at risk patients.   Colorectal cancer (CRC) develops in the colon or rectum, and it accounts for 10% of cancer-related mortality in western world1. Most colorectal cancer begins as a polyp then grow into advanced neoplasia(AN) and, ultimately,
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Cancer encompasses a range of diseases with varying mortality rates. A recent study has shown how cancer mortality rates have changed and influenced life expectancy over 30 years and have uncovered discrepancies in cancer control efforts between different populations.   Cancer is predicted to become the primary cause of global morbidity and mortality, surpassing cardiovascular
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A recent study in JAMA Oncology compared the effectiveness of mammography alone vs. mammography in combination with MRI or ultrasonography in breast cancer screening. The results showed that combinatorial approaches could have a significant impact on detection rates and sensitivity for patients undergoing screening for recurrence.   Breast cancer screening is an indispensable practice in
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Long-term androgen deprivation therapy (ADT) in combination with abiraterone, a selective inhibitor of CYP17, an enzyme needed for androgen production, is associated with significantly higher rates of overall and failure-free survival than ADT alone among men with locally advanced or metastatic prostate cancer. Cancer of the prostate is the most prevalent disease in men, with
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The benefits of sentinel lymph node biopsy in treating skin cancer (melanoma) is well established; however, the value of lymph-node dissection, a procedure in which all nodes located nearby metastasis-positive sentinel nodes are surgically removed, remains controversial. Recently, a phase III clinical trial demonstrated that immediate completion lymph-node dissection is not associated with increased melanoma-specific
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