Month: December 2018

In a recent study published by Nature Medicine, researchers investigated the genetic predispositions to developing dementia. A common form of inherited early-onset dementia that occurs within the frontal and temporal lobes of the brain is often caused by tau, granulin precursor (GRN), and chromosome 9 open reading frame 72 (C9orf72) gene mutations. However, it has
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Scientists made a research breakthrough in understanding the responsible mechanisms of restless leg syndrome.   Restless legs syndrome is a disorder related to sensation and movement. It is a common nervous system condition that causes an overwhelming irresistible urge to move the legs. The uncomfortable sensation usually happens in the evening or nighttime hours when
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Researchers compared the fracture and fall risk in elderly dementia patients taking the antidepressant trazadone or antipsychotic drugs. In Canada, the prevalence of dementia is 25% in individuals over 85 and around 62% amongst residents in continuing-care facilities. The behavioral and psychological symptoms of dementia are very distressing for patients and their caregivers, with almost
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There is a desperate need for a treatment for Alzheimer’s disease. A recent study tested an anti-Alzheimer’s DNA vaccine in mice. Alzheimer’s disease is an irreversible condition that slowly degrades thinking and memory. It currently affects six million Americans, and that number will increase as the population ages. Many scientists think that it is caused
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Published in Nature Genetics, Raj and colleagues investigated the alternate splicing of genes as a potential cause of Alzheimer’s progression. The expression of genes encoded in DNA is responsible for almost the entirety of our body’s functioning. However, the things we need to do—the proteins we need to make and the timing we need to
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A study in healthy adults investigated whether day-to-day variation in sleep quality affects standing balance and increases fall risk. The ability to balance is essential for normal daily activities. Disturbed balance can lead to problems such as feeling dizzy or nauseous and having difficulty walking. It also increases the chances of falling. Maintaining balance involves
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A recent study assessed the impact of singing on the motor function and stress levels of patients with Parkinson’s disease. This past November 2018, researchers attending the Society for Neuroscience revealed their results on a study that determined the benefits of singing for people with Parkinson’s. The study, conducted at Iowa StateUniversity in the United
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Using an animal model, researchers from Oregon investigated how, even after one dose, the hyperactivity associated with cocaine use can alter the brain. Using cocaine creates both physiological and psychological changes. Some of these changes are caused by changes in the nervous system, while others are due to the size, weight, health, and personality of
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Despite the rising number of peanut-allergic children in North America, no FDA approved food allergy treatment is available. A recent phase-3 trial tested a new oral peanut allergy treatment in children and adolescents. There is currently no treatment for allergy symptoms caused by peanut proteins. Peanut-allergic patients are instructed to avoid peanuts and carry at
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An exciting study published in Science Translational Medicine has identified a novel protein which could aid in early diagnosis and lung cancer treatment. It has been established that many tumors rely on a constant glucose supply for supporting their growth. As the cancer cells continue to grow, many cells can adapt and find novel mechanisms
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A clinical trial of a new anti-cholesterol drug has generated promising results in reducing the chances of a second heart attack, unstable angina, or death from coronary heart disease. Acute coronary syndrome is a life-threatening health condition associated with sudden and reduced blood flow to the heart. The resulting under-supply of oxygen to the heart
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A recent study published in Cancer Discovery has highlighted yet another example of how a combination of chemotherapy and immunotherapy could be a way to treat acute myeloid leukemia. Acute myeloid leukemia is a type of cancer that originates in bone marrow, the site for the formation of blood cells in the body. The cancer occurs due to aberrant
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